New tool to distinguish between viral, bacterial infections

01.08.2017. Zanimljivosti

Scientists from the University’s National Institutes of Health-funded Respiratory Pathogens Research Center identified 11 genetic markers in blood that accurately distinguished between viral and bacterial infections (antibiotics help us fight bacterial infections, but aren’t effective and shouldn’t be used to treat viruses). The finding, published in the journal Scientific Reports, is important because physicians don’t have a good way to confirm bacterial infections like pneumonia and more-often-than-not default to an antibiotic.

“It’s extremely difficult to interpret what’s causing a respiratory tract infection, especially in very ill patients who come to the hospital with a high fever, cough, shortness of breath and other concerning symptoms,” said Ann R. Falsey, M.D., lead study author, professor and interim chief of the Infectious Diseases Division at UR Medicine’s Strong Memorial Hospital. “My goal is to develop a tool that physicians can use to rule out a bacterial infection with enough certainty that they are comfortable, and their patients are comfortable, foregoing an antibiotic.”

A group of 94 adults hospitalized with lower respiratory tract infections were recruited to participate in Falsey’s study. The team gathered clinical data, took blood from each patient, and conducted a battery of microbiologic tests to determine which individuals had a bacterial infection (41 patients) and which had a non-bacterial or viral infection (53 patients). Thomas J. Mariani, Ph.D., professor of Pediatrics and Biomedical Genetics at URMC, used complex genetic and statistical analysis to pinpoint markers in the blood that correctly classified the patients with bacterial infections 80 to 90 percent of the time.

“Our genes react differently to a virus than they do to bacteria,” said Mariani, a member of the Respiratory Pathogens Research Center (RPRC). “Rather than trying to detect the specific organism that’s making an individual sick, we’re using genetic data to help us determine what’s affecting the patient and when an antibiotic is appropriate or not.”

Read more here.

Zanimljivosti

06.12.2017. Zanimljivosti
Potential weapons for the battle against antibiotic resistance discovered

The bacterium Pseudomonas aeruginosa can produce specific molecular factors that dramatically increase or decrease an antibiotic's ability to kill Staphylococcus aureus, another bacterium that often co-infects with P. aeruginosa. The findings point to the possibility of new antibiotics employing these factors to enhance antibiotic susceptibility.


01.08.2017. Zanimljivosti
Walnuts may promote health by changing gut bacteria

A new study has found that walnuts in the diet change the makeup of bacteria in the gut, which suggests a new way walnuts may contribute to better health.


Izdavaštvo

Priručnik za vježbe iz opće mikrobiologije

Ovaj sveučilišni priručnik napisalo je petnaestak autora iz desetak visokoškolskih ustanova iz Zagreba i Rijeke, a sadržaj je podijeljen u petnaest, slikama bogato ilustriranih poglavlja u kojima su opisane i obrađene različite bakteriološke, virološke, mikološke, imunološke i molekularno-biološke metode koje se upotrebljavaju u općoj mikrobiologiji koja se studira na nizu različitih fakulteta i visokih škola.

Naruči Više


Veterinarska imunologija

Radi se o vrhunskoj literaturi za potrebe visokoškolske nastave iz veterinarske imunologije. Knjiga je svojim sadržajem namijenjena prvenstveno studentima, ali i veterinarima u praksi i nastavnicima. 
(Iz recenzije)

Naruči Više


Postani član HMD-a

Cilj Društva je okupljanje mikrobiologa i stručnjaka srodnih struka s ciljem unapređenja svih grana mikrobiologije.

Postani član

Šaljite nam novosti

Novosti i zanimljivosti nam šaljite na urednik@hmd-cms.hr.

Skupovi HMD-a

Power of Viruses

Date: May 16-18, 2018

Venue: Poreč, Croatia

It is with great pleasure that we invite you to attend the conference Power of Viruses in Valamar Diamant Hotel, Poreč, Croatia, during May 16-18, 2018.

Posjeti web stranicu


CESAR 2018

Date: 19-22 September 2018

Venue: Sveti Martin na Muri, Croatia

It is our great pleasure to invite you to the 6th Central European Symposium on Antimicrobials and Antimicrobial Resistance, CESAR2018.

Posjeti web stranicu


Arhiva skupova

Ostali skupovi

IWA 10th Eastern European Young Water Professionals Conference

Date: May 7th - 12th, 2018

Venue: Zagreb, Croatia